Online Registration Now Closed
Online registration for 5th annual meeting of the Great Lakes Drug Metabolism Discussion Group is now closed. On-site registration will be available on the morning of May 6th.
Poster Information
The maximum poster size is 6 ft. wide x 4 ft. tall.
Hotel Reservations
The 5th annual meeting of the Great Lakes Drug Metabolism Discussion Group will be held on May 6th and May 7th, 2010 at the Marriott West in St. Louis, Missouri.

You can reserve your room at the discounted rate of $105 per night using Group Code: gldglda at the Marriott West web site.
Meeting Program
Thursday, May 6, 2010
Registration, coffee, and poster setup, 10:00 AM
Welcome, 11:00 AM
Multiple Transport Systems in the BBB: Impact on CNS Drug Delivery, 11:10 AM
William F. Elmquist, Professor and Department Head, Department of Pharmaceutics, College of Pharmacy, University of Minnesota
Probing Mechanisms of Inter-Individual Susceptibility to Toxicants with Population-Based Experimental Approaches, 11:50 AM
Ivan Rusyn, Associate Professor, Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill
Lunch, poster viewing, and sponsor booths, 12:30 PM
Minimally and Noninvasive Clinical CYP3A Phenotyping, 2:00 PM
Evan Kharasch, Director, Division of Clinical and Translational, Research Professor of Anesthesiology, Washington University at St. Louis
Drug Biotransformation in Children: Role of Ontogeny, Pharmacogenetics and Developmental Context, 2:40 PM
J. Steven Leeder, Professor of Pediatrics and Pharmacology,
University of Missouri, Kansas City
Break, 3:20 PM
Drug and Disease Model Based Biologic Drug Development, 3:40 PM
Jenny Chien, Research Advisor, Lilly Research Labs, Eli Lilly & Co.
Quantification of Gemcitabine-DNA Adducts in Patient Blood, a Novel Biomarker, 4:20 PM
Enaksha Wickremsinhe, Principle Research Scientist, Drug Disposition, Eli Lilly
Poster session (author available), sponsor booths, and mixer, 5:00 PM
Dinner, 7:30 PM
Friday, May 7, 2010
Preclinical to Clinical Translation of Tasocitinib (CP-690,550), a JAK Inhibitor, in Rheumatoid Arthritis, 9:00 AM
Martin Dowty, Senior Principal Scientist, Pharmacokinetics Dynamics and Metabolism (PDM), Pfizer
Enabling Compound Progression with Improved Drug-Drug Interaction Predictions, 9:35 AM
Mohamad Shebley, Senior Scientist, Abbott Laboratories
Break, 10:10 AM
Investigation of Metabolism-Mediated Toxicity in Early Development, 10:40 AM
William Humphreys, Bristol-Myers Squibb
Probing the Recognition Signal for Ubiquitination of Suicide-Inactivated Neuronal Nitric Oxide Synthase with a C331A Mutant of the Enzyme, 11:15 AM
Kelly M. Clapp, Graduate Student, University of Michigan
Effects of Valproic Acid on Organic Acid Metabolism in Children: A Metabolic Profiling Study, 11:40 AM
Kristin E. Price, Post-Doc, Children Mercy Hospital
2010 Sponsor/Exhibitor Prospectus
The 2010 GLDMDG Meeting Sponsor/Exhibitor Prospectus is now available for download.