2012 Meeting

//2012 Meeting
2012 Meeting 2016-11-13T19:50:45+00:00

Radisson Plaza Hotel at Kalamazoo Center

Kalamazoo, Michigan
May 3-4, 2012

Meeting Booklet Adobe Reader icon

Thursday, May 3, 2012

Registration, Continental Breakfast, Poster Setup, and Sponsor Booth Setup., 10:00 AM

Welcome., 11:00 AM

In Vitro Approaches to Assess the Enzyme-Suppressing Effects of Therapeutic Proteins., 11:10 AM
Andrew Parkinson, Ph.D.,CEO, XPD Consulting, Shawnee, KS.

Probing P450 Structure-Function Relationships using X-ray Crystallography., 11:50 AM
Eric Johnson, Ph.D., Professor, Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA.

Lunch, Poster Viewing, and Sponsor Booths, 12:30 PM

Clarifying the Importance of CYP2C19 and PON1 in the Mechanism of Clopidogrel Bioactivation and In Vivo Antiplatelet Response., 2:00 PM
Romel Tirona, Ph.D, Assistant Professor, Division of Clinical Pharmacology, Departments of Physiology & Pharmacology and Medicine, The University of Western Ontario, London, Ontario, Canada.

Evaluation of Absorption Mediated Drug-Drug Interactions in the Oncology Setting., 2:40 PM
Joseph Ware, Ph.D., Senior Scientist, Clinical Pharmacology, Genentech, South San Francisco, CA.

Break, 3:20 PM

Nuclear Receptor Regulation of Hydroxysteroid Sulfotransferase (SULT2A): Implications for Metabolic Disease Mechanisms., 3:40 PM
Melissa Runge-Morris, M.D., Director, Institute of Environmental Health Sciences, Wayne State University, Detroit, MI.

Modeling Enzyme-Substrate Interactions of CYP2A6 and CYP2A6*18., 4:20 PM
Patrick Kane, Graduate Student, Walsh University, North Canton, OH.

Mechanism-based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos., 4:40 PM
Jaime D’Agostino, Post-Doc, University of Michigan, Ann Arbor, MI.

Poster Session (Author Available), Sponsor Booths, and Mixer, 5:00 PM

Dinner, 7:00 PM

 

Friday, May 4, 2012

GLDMDG Business Meeting and Sponsor Booth Setup, 7:30 AM

Continental Breakfast and Poster Viewing, 8:00 AM

Metabolite Identification by High Resolution Mass Spectrometry in High Throughput Drug Discovery Settings., 9:00 AM
Jianwei Shen, Ph. D., Senior Scientist, Drug Metabolism, Abbott Laboratories, Abbott Park, IL.

NMR as a Tool in Mitigating Metabolism Issues in Early Discovery., 9:35 AM
Gregory Walker, Senior Principal Scientist, Pharmacokinetics, Dynamics and Metabolism, Pfizer,
Inc., Groton, CT.

Break, 10:10 AM

Application of PBPK Modeling to Drug Discovery., 10:30 AM
Daniel Mudra, Ph.D., Senior Research Scientist, Eli Lilly and Company, Indianapolis, IN.

The Principles of Human Food Safety with Respect to the Development, Commercialization, Evolution (and Metabolism) of Ceftiofur., 11:05 AM
David Gottschall, Ph.D., Research Fellow, Veterinary Medicine Research & Development, Pfizer Animal Health, Kalamazoo, MI.

Closing Remarks, 11:40 AM