Brook Lodge Hotel & Conference Resort
April 27-28, 2006
Thursday, April 27, 2006
Registration, Coffee and Poster Setup, 10:00 AM
Welcome, 11:00 AM
Paul Hollenberg, Ph.D., Chair, Dept. of Pharmacology, University of Michigan, Ann Arbor, MI.
Current Developments and Future Needs in DMPK., 11:15 AM
Gerald Miwa, Ph.D., Vice President, Drug Metabolism & Pharmacokinetics, Millennium Pharmaceuticals Inc., Cambridge, MA.
Why is the Liver Microsomal Cytochrome P450 such a Versatile and Unique Enzyme?, 12:00 PM
Anthony Y. H. Lu, Ph.D., Adjunct Professor, Department of Chemical Biology, College of Pharmacy, Rutgers University, Piscataway, NJ.
Lunch, Poster Viewing, and Sponsor Booths, 12:45 PM
Afternoon Introduction, 2:00 PM
Wendell W. Weber, M.D., Ph.D., Professor Emeritus, Dept. of Pharmacology, University of Michigan, Ann Arbor, MI.
Clinical Pharmacogenetics-Pharmacokinetics in New Chemical Entity Development., 2:15 PM
David Katz, Ph.D., Associate Scientific Director, Abbott Laboratories, Abbott Park, IL.
Pharmacogenetics and CYP2C9-mediated Drug Interactions., 3:00 PM
Timothy S. Tracy, Ph.D., Professor and Department Head, Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN.
Break, 3:45 PM
Hepatic Drug Transporters: Expression, Function, and Pharmacogenetics., 4:00 PM
Richard B. Kim M.D., Professor of Medicine and Pharmacology, Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN.
Can the Rat be used to Predict Human Drug-Drug Interactions?, 4:45 PM
Stephen D. Hall, Ph.D., Professor of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, IN
Poster Session (Author Available), Sponsor Booths, and Mixer, 5:30 PM
Dinner, 7:00 PM
Friday, April 28, 2006
Business Meeting for GLDMDG Committee Members, 7:30 AM
Introduction, 9:00 AM
Yoichi Osawa, Ph.D., Associate Professor, Dept. of Pharmacology, Univ. of Michigan, Ann Arbor, MI.
New Initiatives in Drug Discovery: The Role for DMPK in the Evolving Interplay of Industry, Academia and Government., 9:15 AM
David D. Christ, Ph.D., Consultant, SNC Partners LLC, Newark, DE.
Break, 10:00 AM
Glucuronidation: The Other Major Metabolic Pathway., 10:15 AM
Steven Wrighton, Ph.D., Senior Research Fellow, Drug Disposition, Lilly Research Labs, Indianapolis, IN.
Innovative Early Clinical Strategies to Rapid Decision-Making., 11:00 AM
Joseph Fleishaker, Ph.D., Executive Director, Translational Medicine, Pfizer Global Research & Development, Ann Arbor, MI.
Closing Remarks, 11:45 AM
Joseph Ware, Ph.D., Senior Principal Scientist, Pharmacokinetics, Dynamics, & Metabolism, Pfizer Global Research & Development, Ann Arbor, MI.