Great Lakes Drug Metabolism and Disposition Group


Recent News

2018 Meeting Schedule


The schedule for this year's GLDMDG meeting and other meeting-related information can be viewed on the 2018 meeting page of this website. Online registration for the meeting will be available on Monday, March 12th.


Thursday, May 10, 2018

Registration, Poster Setup, and Sponsor Booth Setup, 10:00 AM

Welcome, 11:00 AM

Challenges and Opportunities in the Application of Translational Sciences to Drug Development, 11:10 AM
Larry Lesko, Ph.D., Professor of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL

The Impact of Cellular Binding Proteins on Metabolic Enzyme Activity, 11:50 AM
Nina Issoherranen, Ph.D., Professor and Vice-Chair of Pharmaceutics, University of Washington, Seattle, WA

Lunch, Students and Postdocs Network with Industry Scientists, View Posters, and Visit Sponsor Booths, 12:30 PM

Protein Structure Based Approaches for Reducing Potential P450 Drug-Drug Interactions, 2:00 PM
Eric Johnson, Ph.D., Professor of Molecular Medicine, Scripps Research Institute, La Jolla, CA

Allosteric Mechanism of Drug-Drug Interactions Mediated by Human Cytochrome P450 CYP3A4, 2:40 PM
Ilia Denisov, Ph.D., Senior Research Scientist, Department of Biochemistry. University of Illinois, Urbana, IL

Break, 3:20 PM

Projection of Plasma Metabolite-to-Parent Drug Ratio in Human, 3:40 PM
Scott Obach, Ph.D., Senior Research Fellow, Pharmacokinetics, Dynamics, & Drug Metabolism Department, Pfizer Inc., Groton, CT

Drug Discovery Challenges for Developing a Treatment for Glioblastoma, 4:20 PM
Laurent Salphati, Pharm.D., Ph.D. Principal Scientist, Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA

Poster Session (Author Available), Sponsor Booths, and Mixer, 5:00 PM

Dinner, 7:00 PM


Friday, May 11, 2018

GLDMDG Business Meeting, 7:30 AM

Continental Breakfast, Poster Viewing and Sponsor Booth Setup, 7:30 AM

Solute Carriers as Modulators of Chemotherapy Toxicity, 9:00 AM
Alex Sparreboom, Ph.D., Professor of Pharmaceutics, The Ohio State University, Columbus, OH

The Dose Makes the Drug: Strategies to Assess and Improve the Probability of Success for Small Molecule and Antibody Drug Candidates, 9:40 AM
Cory Kalvas, Ph.D., Senior Principal Research Scientist, AbbVie, Chicago, IL

Break, 10:20 AM

Non-CYP Metabolism: Lost in Translation, 10:40 AM
Michael Mohutsky, Ph.D., Principal Research Scientist, Eli Lilly and Co., Indianapolis, IN

Student Abstract Award Winner, 11:20 AM

Postdoc Abstract Award Winner, 11:35 AM

Closing Remarks, 11:50 AM