Great Lakes Drug Metabolism and Disposition Group


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2019 Meeting Schedule

The schedule for this year's GLDMDG meeting is now set. Other meeting-related information can be viewed on the 2019 meeting page of this website. Online registration for the meeting will be available in mid to late February.

Thursday, 9 May 2019

10:00 AM Registration, Poster Setup, and Sponsor Booth Setup

11:00 AM Welcome, Paul F Hollenberg, Ph.D., Department of Pharmacology, University of Michigan, Ann Arbor, MI

11:10 AM Quo Vadis, Cytochrome P450? Successes, Advances, and Future Research, Frederick P Guengerich, Ph.D., Tadashi Inagami Professor of Biochemistry, Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN

11:50 AM Hepatic P450 Degradation: Physiological, Pathological and Therapeutic Relevance, Maria Almira Correia, Ph.D., Professor of Pharmacology, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA

12:30 PM Lunch, Students and Postdocs Network with Industry Scientists, View Posters, and Visit Sponsor Booths

2:00 PM Application Of Intestinal Organoid Cell Culture in Drug Metabolism and Toxicity Studies, Shujuan Chen, Ph.D., DABT, Assistant Professor, University of California, San Diego, La Jolla, CA

2:40 PM Challenges and Recent Progress Toward In Vitro-to-In Vivo Extrapolation of Transporter-Mediated Hepatic Clearance, Bridget Morse, Pharm.D., Ph.D., Senior Research Scientist, Eli Lilly, Indianapolis, IN

3:20 PM Break

3:40 PM Transporter Endogenous Biomarkers for Prediction of Clinical Drug-Drug Interactions, Kenta Yoshida, Ph.D., Scientist, Clinical Pharmacology, Genentech Research and Early Development, South San Francisco, CA

4:20 PM IVIVE-PBPK Modeling of Heterogeneous Drug Penetration into Human Brain Tumors, Jing Li, Ph.D., Associate Professor, Department of Oncology, Wayne State University School of Medicine, Detroit, MI

5:00 PM Poster Session (Author Available), Sponsor Booths, and Mixer

7:00 PM Dinner

Friday, 10 May 2019

7:30 AM GLDMDG Business Meeting

7:30 AM Continental Breakfast, Poster Viewing and Sponsor Booth Setup

9:00 AM Lessons from Targeted Covalent Bruton’s Tyrosine Kinase Inhibitors, Acalabrutinib and its Major Metabolite: Disposition of a Unique, Low Reactivity, High Selectivity Warhead, Terry Podoll, Ph.D., Principal Consultant, Increased Value Pharmaceutical Outsourcing, LLC, Seattle, WA

9:40 AM Discovery and Development of Venetoclax from the DMPK Perspective, Jens Sydor, Senior Director, DMPK-BA Development Sciences, Abbvie, North Chicago, IL

10:20 AM Break

10:40 AM Drug Metabolism by Gut Bacteria, Hyun Young Jeong, Pharm.D., Ph.D., Professor of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, IL

11:20 AM Student Abstract Award Winner Presentation

11:35 AM Postdoc Abstract Award Winner Presentation

11:50 AM Closing Remarks

Howard Millermeeting, schedule, 2019