Great Lakes Drug Metabolism and Disposition Group

2011 Meeting

Schedule &
Meeting Booklet


2011 Meeting

Madison, Wisconsin (Dori/Wikimedia Commons, Creative Commons)

Madison, Wisconsin (Dori/Wikimedia Commons, Creative Commons)

Monona Terrace Convention Center

Madison, Wisconsin
May 10-11, 2011
Meeting Booklet


Tuesday, May 10, 2011

Registration, Continental Breakfast, Poster Setup, and Sponsor Booth Setup, 10:00 AM

Welcome, 11:00 AM

Investigation of the Role of Reactive Metabolites in the Mechanism of Idiosyncratic Drug Reactions., 11:10 AM
Jack Uetrecht, M.D., Ph.D., University of Toronto, Toronto, Ontario.

Drugs Dancing Together: The Origins of “Cooperativity” in Drug-Drug Interactions., 11:50 AM
Stephen Sligar, Ph.D., University of Illinois, Urbana, Illinois.

Lunch, Poster Viewing, and Sponsor Booths, 12:30 PM

Translating Genotype to Phenotype: Genetic Variability of DMEs., 2:00 PM
Andrea Gaedigk, Ph.D., Children’s Mercy Hospital, Kansas City, Missouri.

Pharmacogenetics in Anti-Cancer Drug Development., 2:40 PM
Jill M. Kolesar, Pharm.D., BCPS, FCCP, University of Wisconsin, Madison, Wisconsin.

Break, 3:20 PM

Regulation of Drug Metabolism in Infectious Diseases. Are Cytokines the Whole Story?, 3:40 PM
Edward T. Morgan, Ph.D., Emory University, Atlanta, Georgia.

Ontogeny of Human Hepatic Drug Metabolizing Enzymes., 4:20 PM
Ron Hines, Ph.D., Medical College of Wisconsin, Milwaukee, Wisconsin and Children’s Hospital and Health Systems, Milwaukee, Wisconsin.

Poster Session (Author Available), Sponsor Booths, and Mixer, 5:00 PM

Dinner, 7:00 PM  


Wednesday, May 11, 2011

GLDMDG Business Meeting, 7:30 AM

Continental Breakfast and Poster Viewing, 8:00 AM

New Models in Drug Development: Human Induced Pluripotent Stem (iPS) Cells and their Derivatives., 9:00 AM
Vanessa Ott, Ph.D. Cellular Dynamics International, Madison, Wisconsin.

Impact of Protein Binding on Cell Penetration and PK/PD of Small Molecules., 9:35 AM
J. Cory Kalvass, Abbott Laboratories, Abbott Park, Illinois.

Break, 10:10 AM

Optimizing ADME Properties of Molecules in Early Drug Discovery., 10:30 AM
Jeffrey W. Cramer, Lilly Research Laboratories, Indianapolis, Indiana.

Cytochrome P450 2E1 Competes with Cytochrome P450 2B4 for Limited NADPH-Cytochrome P450 Reductase., 11:05 AM
Cesar Kenaan, University of Michigan, Ann Arbor, Michigan.

Individual Variability in the Detoxification of Carcinogenic Arylhydroxylamines in Human Breast., 11:30 AM
James Sacco, University of Wisconsin, Madison, Wisconsin.

Closing Remarks, 11:55 AM