Great Lakes Drug Metabolism and Disposition Group

2017 Meeting

Schedule &
Meeting Booklet


2017 Meeting

Kalamazoo, Michigan (Mxobe/Wikimedia Commons, Creative Commons)

Kalamazoo, Michigan (Mxobe/Wikimedia Commons, Creative Commons)

Bernhard Center, Western Michigan University

Kalamazoo, Michigan
May 4-5, 2017
Meeting Booklet


Thursday, May 4, 2017

Registration, Continental Breakfast, Poster Setup, and Sponsor Booth Setup, 10:00 AM

Welcome, 11:00 AM

P450 Structure-Function Studies at Large Scale: Application to Pharmacogenomics., 11:10 AM
Allan Rettie, Ph.D., Professor, Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle.

Genetic and Functional Studies of Chemotherapy-Induced Peripheral Neuropathy., 11:50 AM
Deanna Kroetz, Ph.D., Professor, Departments of Biopharmaceutical Sciences and Pharmaceutical Chemistry, University of California, San Francisco.

Lunch, Students and Postdocs Network with Industry Scientists, View Posters, and Visit Sponsor Booths, 12:30 PM

Quantitative Proteomic Analysis for Membrane Proteins in Healthy and Disease Tissues to Delineate Drug Clearance and Intracellular Disposition., 2:00 PM
Yurong Lai, Ph.D., Director of Drug Metabolism, Gilead Sciences, Inc., Foster City, CA.

Transporters in Xeno-Endobiotic Drug Interactions., 2:40 PM
Eve-Irene Lepist, Ph.D., Sr. Research Scientist II, Gilead Sciences, Inc., Foster City, CA.

Break, 3:20 PM

Cytochrome P450 3A7: Fetal Drug Metabolism., 3:40 PM
Emily Scott, Ph.D., Professor, Medicinal Chemistry and Professor, Pharmacology, University of Michigan, Ann Arbor.

Structural Plasticity in Drug Metabolizing P4503A4., 4:20 PM
Tom Poulos, Ph.D., Chancellor’s Professor of Biochemistry, Chemistry, and Pharmaceutical Sciences, University of California, Irvine.

Poster Session (Author Available), Sponsor Booths, and Mixer, 5:00 PM

Dinner, 7:00 PM


Friday, May 5, 2017

GLDMDG Business Meeting and Sponsor Booth Setup, 7:30 AM

Continental Breakfast and Poster Viewing, 7:30 AM

Pharmacologically Active Acyl Glucuronide Metabolites of Indole-3-carboxylic Acid-based AMP Kinase Activators., 9:00 AM
Amit Kalgutkar, Ph.D., Research Fellow at Pfizer and Adjunct Professor, Department of Pharmacy and Biomedical Sciences, University of Rhode Island.

Gut Microbiome: A Novel Frontier in Xenobiotic Biotransformation., 9:40 AM
Julia Yue Cui, Ph.D., Assistant Professor, Department of Environmental and Occupational Health Sciences and Center for Ecogenetic and Environmental Health, University of Washington, Seattle.

Break, 10:20 AM

Non-CYP Drug Metabolism Pathways and Selected Case Studies., 10:40 AM
David Stresser, Ph.D., Principal Research Scientist, AbbVie, North Chicago, Illinois.

In Vitro and In Vivo Functional Testing of SNPs in the 3’UTR of CYP2B., 11:20 AM
Kimberly Burgess, Graduate Student, Indiana University, School of Medicine, Indianapolis.

Posttranslational Regulation of CYP2J2 by Nitric Oxide., 11:35 AM
Ji Won Park, Ph.D., Postdoctoral Fellow, Department of Pharmacology, Emory University, School of Medicine, Atlanta, Georgia.

Closing Remarks, 11:50 AM