Great Lakes Drug Metabolism and Disposition Group

2019 Meeting

Meeting Schedule and Other Information


2019 Meeting

This year’s GLDMDG meeting is sold out. Online registration is now closed and on-site registration will not be available. The GLDMDG steering committee looks forward to hosting the 200+ attendees and 30+ sponsors in Ann Arbor on May 9th and 10th.




Thursday, 9 May 2019

9:00 AM Registration, Continental Breakfast, Poster Setup, and Sponsor Booth Setup

11:00 AM Welcome, Paul F Hollenberg, Ph.D., Department of Pharmacology, University of Michigan, Ann Arbor, MI

11:10 AM Quo Vadis, Cytochrome P450? Successes, Advances, and Future Research, Frederick P Guengerich, Ph.D., Tadashi Inagami Professor of Biochemistry, Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN

11:50 AM Hepatic P450 Degradation: Physiological, Pathological and Therapeutic Relevance, Maria Almira Correia, Ph.D., Professor of Pharmacology, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA

12:30 PM Lunch, Students and Postdocs Network with Industry Scientists (South Atrium), View Posters, and Visit Sponsor Booths

2:00 PM Application Of Intestinal Organoid Cell Culture in Drug Metabolism and Toxicity Studies, Shujuan Chen, Ph.D., DABT, Assistant Professor, University of California, San Diego, La Jolla, CA

2:40 PM Challenges and Recent Progress Toward In Vitro-to-In Vivo Extrapolation of Transporter-Mediated Hepatic Clearance, Bridget Morse, Pharm.D., Ph.D., Senior Research Scientist, Eli Lilly, Indianapolis, IN

3:20 PM Break

3:40 PM Transporter Endogenous Biomarkers for Prediction of Clinical Drug-Drug Interactions, Kenta Yoshida, Ph.D., Scientist, Clinical Pharmacology, Genentech Research and Early Development, South San Francisco, CA

4:20 PM IVIVE-PBPK Modeling of Heterogeneous Drug Penetration into Human Brain Tumors, Jing Li, Ph.D., Associate Professor, Department of Oncology, Wayne State University School of Medicine, Detroit, MI

5:00 PM Poster Session (Author Available), Sponsor Booths, and Mixer

7:30 PM Dinner (Holiday Inn, 3600 Plymouth Rd, Ann Arbor, Michigan)

Friday, 10 May 2019

7:30 AM GLDMDG Business Meeting (Room G064)

7:30 AM Continental Breakfast, Poster Viewing and Sponsor Booth Setup

9:00 AM Lessons from Targeted Covalent Bruton’s Tyrosine Kinase Inhibitors, Acalabrutinib and its Major Metabolite: Disposition of a Unique, Low Reactivity, High Selectivity Warhead, Terry Podoll, Ph.D., Principal Consultant, Increased Value Pharmaceutical Outsourcing, LLC, Seattle, WA

9:40 AM Discovery and Development of Venetoclax from the DMPK Perspective, Dan Bow, Ph.D., Senior Principal Research Scientist, DMPK-BA Development Sciences, AbbVie, North Chicago, IL

10:20 AM Break

10:40 AM Drug Metabolism by Gut Bacteria, Hyun Young Jeong, Pharm.D., Ph.D., Professor of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, IL

11:20 AM Contribution of Organic Cation Transporter 3 (OCT3) to Doxorubicin-Induced Cardiotoxicity, Kevin M. Huang, B.S., Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH, Student Abstract Award Winner

11:35 AM Insight of Cytochrome P450 24A1 and Adrenodoxin Interaction as Modulated by Carbon-25 Hydroxylation of Vitamin-D Ligand, Amit Kumar, Ph.D., Department of Biochemistry, State University of New York at Buffalo, Buffalo, NY, Postdoc Abstract Award Winner

11:50 AM Closing Remarks

Registration Fees


Registration Type

Student/Postdoc with Poster (must be primary presenter)



February 27 to April 19 Free $50 $150
April 20 to April 26  $50
After April 26 $100 $300

Poster Information

The submission deadline for all posters is Friday, April 26th. If you plan to present a poster at this year's meeting, you will be asked to enter your poster's title, authors, and abstract during the registration process. Plain text (.txt), rich text (.rtf), Adobe Acrobat (.pdf), and Microsoft Word (.doc or .docx) are acceptable file formats for your abstract. The maximum poster size is 48 inches wide x 36 inches tall and a poster template is provided as a Microsoft PowerPoint file (see link below).

GLDMDG Poster Template

Students and postdocs who register for the meeting and submit a poster by Friday, April 19th will have their registration fee waived. The registration fee for students and postdocs increases to $50 after April 19th. During registration process, each student/postdoc with a poster can opt-in for the opportunity to give an oral presentation of their poster contents. One student and one postdoc will be nominated by the GLDMDG steering committee to give oral presentations. Each nominated presenter will receive a travel award of $250 to cover expenses. Posters must be submitted by Friday, April 19th to be considered for an award. Nominated presenters will be notified by a GLDMDG committee member no later than Friday, April 26th.

Hotel Information

Holiday Inn Ann Arbor - Near University of Michigan
3600 Plymouth Rd, Ann Arbor, Michigan 48105
Phone: +1 734-769-9800
Reservations: +1 877-666-3243

A block of rooms has been reserved at the Holiday Inn for the GLDMDG meeting. The room rate starts at $119/night + taxes. Room reservations can be made at the hotel's room reservation page or by calling +1 877-666-3243. Use the group code GLM and make your reservation before April 25th to receive the discounted room rate. The Holiday Inn will offer free shuttle service between the hotel and the NCRC. The hotel shuttle schedule will be determined closer to the meeting date.

Event Parking and Transportation


NC100 Parking Structure
$10 per day, cash only

NC99 Parking Lot (Visitor Parking)
$10 per day, credit card only

Shuttle Bus (Golden Limousine, Inc.)
A free shuttle service will be available to transport registered attendees between the Holiday Inn and NCRC during the morning of both meeting days.

May 9: Pick up at the Holiday Inn and drop off at NCRC Building 18. Continuous service from 9:00 AM until 11:00 AM.

May 10: Pick up at the Holiday Inn and drop off at NCRC Building 18. Continuous service from 6:30 AM until 9:00 AM.

Charter Bus (University of Michigan)
A free charter bus service will be provided to transport attendees between the Holiday Inn, NCRC, and downtown Ann Arbor during the evening of May 9th. The bus schedule will be posted at the meeting and printed in the meeting booklet.

Sponsorship Opportunities

Sponsorship opportunities are available for this year's GLDMDG meeting. Four sponsorship levels are available and each level's benefits are described in the 2019 GLDMDG Sponsorship Prospectus.

Sponsorship Level

Amount ($USD)

Major Benefactor 5000
Gold 2500
Silver 1000
Bronze 500

Area Attractions