Great Lakes Drug Metabolism and Disposition Group

2019 Meeting

Meeting Schedule and Other Information


2018 Meeting

 Skyline Indianapolis, Indiana ( Jimmy Baikovicius /Flickr, Creative Commons)

Skyline Indianapolis, Indiana (Jimmy Baikovicius/Flickr, Creative Commons)

Registration for this year's GLDMDG meeting is now closed. No on-site registration will be available for the meeting.

Location & Dates

Sheraton Indianapolis City Centre Hotel
Indianapolis, Indiana
May 10-11, 2018



Thursday, May 10, 2018

Registration, Poster Setup, and Sponsor Booth Setup, 10:00 AM

Welcome, 11:00 AM

Applications of Translational Science in Drug Development and Regulatory Agencies – Challenges and Opportunities, 11:10 AM
Larry Lesko, Ph.D., Professor of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL

The Impact of Cellular Binding Proteins on Metabolic Enzyme Activity, 11:50 AM
Nina Issoherranen, Ph.D., Professor and Vice-Chair of Pharmaceutics, University of Washington, Seattle, WA

Lunch, Students and Postdocs Network with Industry Scientists, View Posters, and Visit Sponsor Booths, 12:30 PM

Protein Structure Based Approaches for Reducing Potential P450 Drug-Drug Interactions, 2:00 PM
Eric Johnson, Ph.D., Professor of Molecular Medicine, Scripps Research Institute, La Jolla, CA

Allosteric Mechanism of Drug-Drug Interactions Mediated by Human Cytochrome P450 CYP3A4, 2:40 PM
Ilia Denisov, Ph.D., Senior Research Scientist, Department of Biochemistry. University of Illinois, Urbana, IL

Break, 3:20 PM

Projection of Plasma Metabolite-to-Parent Drug Ratio in Human, 3:40 PM
Scott Obach, Ph.D., Senior Research Fellow, Pharmacokinetics, Dynamics, & Drug Metabolism Department, Pfizer Inc., Groton, CT

Drug Discovery Challenges for Developing a Treatment for Glioblastoma, 4:20 PM
Laurent Salphati, Pharm.D., Ph.D. Principal Scientist, Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA

Poster Session (Author Available), Sponsor Booths, and Mixer, 5:00 PM

Dinner and Special Presentation, 7:00 PM


Friday, May 11, 2018

GLDMDG Business Meeting, 7:30 AM

Continental Breakfast, Poster Viewing and Sponsor Booth Setup, 7:30 AM

Solute Carriers as Modulators of Chemotherapy Toxicity, 9:00 AM
Alex Sparreboom, Ph.D., Professor of Pharmaceutics, The Ohio State University, Columbus, OH

The Dose Makes the Drug:  Strategies to Assess and Improve the Probability of Success for Small Molecule and Antibody Drug Candidates, 9:40 AM
Cory Kalvas, Ph.D., Senior Principal Research Scientist, AbbVie, Chicago, IL

Break, 10:20 AM

Non-CYP Metabolism: Lost in Translation, 10:40 AM
Michael Mohutsky, Ph.D., Principal Research Scientist, Eli Lilly and Co., Indianapolis, IN

Differential Microbiota in the Gut Modulates Susceptibility to Acetaminophen-Induced Hepatotoxicity in C57BL/6 Mice, 11:20 AM
Student Abstract Award Winner: Sungjoon Cho, Graduate Student, University of Illinois at Chicago

Physiologically-Based Pharmacokinetic Model Incorporating Extrahepatic Glucuronidation Predicts Integrase Inhibitor Pharmacokinetics, 11:35 AM
Postdoc Abstract Award Winner: Stephanie Liu, Pharm.D., Clinical Pharmacology Fellow, Indiana University School of Medicine

Closing Remarks, 11:50 AM

Eli Lilly Tour for Students and Postdocs, 12:15 PM

Registration Fees

Registration Type Fee ($USD)
Standard 150
Student/Postdoc 50
Student/Postdoc with Poster (must be primary presenter and register by Friday, April 20th; fee increases to $50 after April 20th deadline) 0

Poster Information

The submission deadline for all posters is Friday, April 27th. If you plan to present a poster at this year's meeting, you will be asked to enter your poster's title, authors, and abstract during the online registration process.  Plain text (.txt), rich text (.rtf), Adobe Acrobat (.pdf), and Microsoft Word (.doc or .docx) are acceptable file formats for your abstract submission.

The maximum poster size is 48 inches wide x 36 inches tall and a Microsoft PowerPoint file is available for use as a poster template.

Students and postdocs who register for the meeting and submit a poster by Friday, April 20th will have their registration fee waived (fee increases to $50 after April 20th deadline). 

During the registration process, students and postdocs with posters will be asked whether or not their posters should be considered for podium presentations. One student and one postdoc will be nominated by the GLDMDG steering committee to give oral 10-15 minute presentations of their poster contents.  Each nominated presenter will receive a travel award of $250 to cover expenses.  Posters must be submitted by Friday, April 20th to be considered for an award.  Nominated presenters will be notified by a GLDMDG committee member no later than Friday, April 27th.

Hotel Information

Sheraton Indianapolis City Centre Hotel
31 W Ohio Street
Indianapolis, IN 46204
Phone: +1.317.635.2000

A block of rooms has been reserved at the hotel for the GLDMDG meeting. The discounted room rate is $159/night + taxes (1 king bed or 2 double beds). Room reservations can be made by following this link.

The discounted room rate is valid through April 20th.

Sponsorship Opportunities

Sponsorship opportunities are available for this year's GLDMDG meeting. Four sponsorship levels are available and each level's benefits are described in the 2018 GLDMDG Sponsorship Prospectus.

Sponsorship Level Amount ($USD)
Major Benefactor 5000
Gold 2500
Silver 1000
Bronze 500

Area Attractions