Great Lakes Drug Metabolism and Disposition Group


Recent News

21st DMPK Land O'Lakes Meeting

The 21st DMPK Land O'Lakes Meeting will be held in Madison, Wisconsin from September 17th through the 20th. Learn about the new DDI guidances and EMA FIH guidelines. As a GLDMG member, you will receive a 20% discount when you register for the meeting (Use code GLDMG2018). Graduate students and post-docs who present a poster can attend for FREE! Poster submission guidelines can be found on the course page. Learn more about this meeting at

Online Registration is Now Available

The GLDMDG steering committee is pleased to invite you to attend the 13th annual meeting of the Great Lakes Drug Metabolism and Disposition Group to be held on May 10-11, 2018 at the Sheraton Indianapolis City Centre Hotel in Indianapolis, Indiana.  

Confirmed speakers include: Larry Lesko from the University of Florida, Nina Issoherranen from the University of Washington, Eric Johnson from Scripps Research Institute, Ilia Denisov from the University of Illinois, Scott Obach of Pfizer, Laurent Salphati from Genentech, Alex Sparreboom from The Ohio State University, Cory Kalvas of AbbVie, and Michael Mohutsky of Eli Lilly.

Navigate to the 2018 meeting page of this website to view additional details about this year's meeting.

Registration powered by RegOnline
2018 Meeting Schedule

The schedule for this year's GLDMDG meeting and other meeting-related information can be viewed on the 2018 meeting page of this website. Online registration for the meeting will be available on Monday, March 12th.


Thursday, May 10, 2018

Registration, Poster Setup, and Sponsor Booth Setup, 10:00 AM

Welcome, 11:00 AM

Challenges and Opportunities in the Application of Translational Sciences to Drug Development, 11:10 AM
Larry Lesko, Ph.D., Professor of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL

The Impact of Cellular Binding Proteins on Metabolic Enzyme Activity, 11:50 AM
Nina Issoherranen, Ph.D., Professor and Vice-Chair of Pharmaceutics, University of Washington, Seattle, WA

Lunch, Students and Postdocs Network with Industry Scientists, View Posters, and Visit Sponsor Booths, 12:30 PM

Protein Structure Based Approaches for Reducing Potential P450 Drug-Drug Interactions, 2:00 PM
Eric Johnson, Ph.D., Professor of Molecular Medicine, Scripps Research Institute, La Jolla, CA

Allosteric Mechanism of Drug-Drug Interactions Mediated by Human Cytochrome P450 CYP3A4, 2:40 PM
Ilia Denisov, Ph.D., Senior Research Scientist, Department of Biochemistry. University of Illinois, Urbana, IL

Break, 3:20 PM

Projection of Plasma Metabolite-to-Parent Drug Ratio in Human, 3:40 PM
Scott Obach, Ph.D., Senior Research Fellow, Pharmacokinetics, Dynamics, & Drug Metabolism Department, Pfizer Inc., Groton, CT

Drug Discovery Challenges for Developing a Treatment for Glioblastoma, 4:20 PM
Laurent Salphati, Pharm.D., Ph.D. Principal Scientist, Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA

Poster Session (Author Available), Sponsor Booths, and Mixer, 5:00 PM

Dinner, 7:00 PM


Friday, May 11, 2018

GLDMDG Business Meeting, 7:30 AM

Continental Breakfast, Poster Viewing and Sponsor Booth Setup, 7:30 AM

Solute Carriers as Modulators of Chemotherapy Toxicity, 9:00 AM
Alex Sparreboom, Ph.D., Professor of Pharmaceutics, The Ohio State University, Columbus, OH

The Dose Makes the Drug: Strategies to Assess and Improve the Probability of Success for Small Molecule and Antibody Drug Candidates, 9:40 AM
Cory Kalvas, Ph.D., Senior Principal Research Scientist, AbbVie, Chicago, IL

Break, 10:20 AM

Non-CYP Metabolism: Lost in Translation, 10:40 AM
Michael Mohutsky, Ph.D., Principal Research Scientist, Eli Lilly and Co., Indianapolis, IN

Student Abstract Award Winner, 11:20 AM

Postdoc Abstract Award Winner, 11:35 AM

Closing Remarks, 11:50 AM

2018 Sponsorship Prospectus

The GLDMDG steering committee is finalizing the speaker lineup for the 2018 GLDMDG meeting.  Sponsorship opportunities are available for this meeting.  The meeting will be held on May 10th and 11th, 2018 at the Sheraton Indianapolis City Centre Hotel in Indianapolis, Indiana. Four sponsorship levels are available:

  • Major Benefactor – $5000
  • Gold – $2500
  • Silver – $1000
  • Bronze – $500

The benefits of each sponsorship level are described in the 2018 GLDMDG Sponsorship Prospectus. Additional information about the meeting will be posted soon on this website.

2018 GLDMDG Meeting Announcement
 Indianapolis Central Canal, Indianapolis, Indiana (Daniel Schwen/Wikimedia Commons, Creative Commons)

Indianapolis Central Canal, Indianapolis, Indiana (Daniel Schwen/Wikimedia Commons, Creative Commons)

The GLDMDG steering committee would like to thank this year's attendees and sponsors for contributing to another successful meeting. We hope to see you next year at our 13th annual meeting in Indianapolis, Indiana on May 10 & 11, 2018.

Howard Miller2018, meeting