Great Lakes Drug Metabolism and Disposition Group

2013 Meeting

Schedule &
Meeting Booklet


2013 Meeting

Toledo, Ohio (NorthernMagnolia/Wikimedia Commons, Creative Commons)

Toledo, Ohio (NorthernMagnolia/Wikimedia Commons, Creative Commons)

The Hotel @ UTMC

Toledo, Ohio
May 9-10, 2013
Meeting Booklet


Thursday, May 9, 2013

Registration, Continental Breakfast, Poster Setup and Sponsor Setup, 10:00 AM

Welcome, 11:00 AM

Predicting Drug Disposition and Drug Dosing Parameters for New Molecular Entities., 11:10 AM
Les Benet, Ph.D., Professor, Dept. of Pharmaceutical Chemistry, School of Pharmacy, UCSF.

What Is the Purpose of Human ADME Studies?, 11:50 AM
Ron White, Ph.D, President, White Global Pharma Consultants, LLC.

Lunch, Poster Viewing, and Sponsor Booths, 12:30 PM

Bile Acid Therapy for Liver Diseases and Diabetes., 2:00 PM
John Chiang, Ph.D., Professor, Dept. of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University.

Glucuronidation: Beyond Drug Metabolism, An Unexploited Pharmacological Target for Endocrine and Metabolic Diseases., 2:40 PM
Olivier Barbier, Ph.D., Assistant Professor, Laboratory of Molecular Pharmacology, Université Laval.

Break, 3:20 PM

Biological Consequences of Reactive Metabolites and the Role of Hsp90/Hsp70 Chaperones., 3:40 PM
Yoichi Osawa, Ph.D.,Professor, Dept. of Pharmacology, University of Michigan.

Gamma-hydroxybutyric acid (GHB) Toxicokinetics and Toxicodynamics: Role of Monocarboxylate Transporters., 4:20 PM
Marilyn Morris, Ph.D., Professor, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo.

Poster Session (Author Available), Sponsor Booths and Mixer, 5:00 PM

Dinner, 7:00 PM  


Friday, 10 May 2013

GLDMDG Business Meeting, 7:30 AM

Continental Breakfast and Poster Viewing, 8:00 AM

Virtues of Virtual ADME Models in Drug Discovery: Reality or Delusion?, 9:00 AM
Prashant Desai, Ph.D., Senior Research Scientist Computational ADME-Toxicology Group, Eli Lilly and Company.

Saving a Drug Candidate: A Case Study of Cyclic Tertiary Amine Metabolism and its Association with Adverse Events., 9:35 AM
Anthony Lee, Ph.D., Group Leader, AbbVie

Break, 10:10 AM

Parasiticide Discovery and Development and the Role of Drug Delivery and Metabolism (from the Parasitologist's Perspective)., 10:30 AM
Douglas Rugg, Ph.D., Director, Antiparasitics Development, Zoetis.

Hydroxylation versus N-Dechloroethylation of Cyclophosphamide by Human Cytochrome P450s., 11:05 AM
Diane Calinski, Graduate Student, University of Michigan.

Application of Hydration Sites in Pharmacophore-Based Virtual Screening., 11:25 AM
Bingjie Hu, Graduate Student, Purdue University.

Closing Remarks, 11:45 AM