Great Lakes Drug Metabolism and Disposition Group

2016 Meeting

Schedule &
Meeting Booklet


2016 Meeting

Grant Park, Chicago, Illinois (Diego Delso/Wikimedia Commons, Creative Commons)

Grant Park, Chicago, Illinois (Diego Delso/Wikimedia Commons, Creative Commons)

Hilton Rosemont/Chicago O’Hare Hotel

Rosemont, Illinois
May 5-6, 2016
Meeting Booklet


Thursday, May 5, 2016

Registration, Continental Breakfast, Poster Setup, and Sponsor Booth Setup, 10:00 AM

Welcome, 11:00 AM

Cytochrome P450 Structure, Dynamics, and Specificity., 11:10 AM
Paul Ortiz de Montellano, PhD, Professor, Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco.

Systems Pharmacology Modeling to Predict Drug-Induced Liver Injury: Hype or Hope?, 11:50 AM
Kim Brouwer, PharmD, PhD, Distinguished Professor, Division of Pharmacotherapy and Experimental Therapeutics, School of Pharmacy, Associate Dean for Research and Graduate Education, University of North Carolina at Chapel Hill.

Lunch, Students and Postdocs Network with Industry Scientists, View Posters, and Visit Sponsor Booths, 12:30 PM

The Outlier in All of Us: Implementing Pharmacogenomics in 2016., 2:00 PM
Peter H. O’Donnell, MD, Assistant Professor, Department of Medicine, University of Chicago.

Unraveling the Mysteries of Predicting Human Pharmacokinetics of Targeted Covalent Inhibitors., 2:40 PM
Mike Zientek, MS, Associate Research Fellow, Pharmacokinetics Dynamics & Metabolism, Pfizer.

Break, 3:20 PM

A View of ADME through the MALDI Imaging MS Looking Glass., 3:40 PM
Steve Castellino, PhD, ‎‎Director, Imaging MS and DMPK, GlaxoSmithKline.

Evaluating the Biodistribution of Biologics using Molecular Imaging., 4:20 PM
John Beaver, PhD, Research Fellow & Head, Translational Imaging, AbbVie.

Poster Session (Author Available), Sponsor Booths, and Mixer, 5:00 PM

Dinner, 7:00 PM


Friday, May 6, 2016

GLDMDG Business Meeting and Sponsor Booth Setup, 7:30 AM

Continental Breakfast and Poster Viewing, 7:30 AM

Predicting the Effect of Disease on Drug Exposure., 9:00 AM
Maria Posada, PhD, Research Scientist, Lilly Research Laboratories.

What We Understand of the Properties of Circulating Metabolites., 9:40 AM
Cyrus Khojasteh, PhD, Associate Director, Drug Metabolism & Pharmacokinetics, Genentech.

Break, 10:20 AM

Biomeasures and the Characterization of ADCs – The Expanding Role of DMPK Bioanalysis in Drug Discovery., 10:40 AM
Gary Jenkins, PhD, Senior Group Leader, AbbVie.

Nitric Oxide Stimulates CYP51A1 Down Regulation., 11:20 AM
Aria Byrd, Emory University, Student Presentation.

Influence of Carboxylesterase 1 Genetic Polymorphisms on the Activation of Dabigatran Etexilate., 11:35 AM
Jian Shi, PhD, University of Michigan, Post-Doc Presentation.

Closing Remarks, 11:50 AM